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Creutzfeldt-Jakob Disease
What Are Transplant Infections?
After an organ or stem-cell transplant, the immune system cannot respond normally, increasing the risk of various infections. These may include viral infections, bacterial illnesses, parasitic conditions, and fungal diseases. Many of these infections are preventable or manageable when overseen by an experienced infectious disease team. Our goal at SSRC is to identify risks before symptoms appear, provide immediate care when infections develop, and support patients through long-term recovery.
Types of CJD
- Sporadic CJD (sCJD): The most common form, with no identifiable cause.
- Genetic/Familial CJD (fCJD):Caused by inherited mutations in the PRNP gene.
- Variant CJD (vCJD): Linked to contaminated beef exposure; extremely rare.
- Iatrogenic CJD: Transmitted through certain medical procedures (now exceedingly uncommon due to global safety protocols).
Symptoms of CJD
Cognitive & Behavioral Symptoms
- Memory loss
- Confusion and disorientation
- Personality or behavior changes
- Difficulty concentrating
Movement & Coordination Symptoms
- Unsteady gait
- Muscle stiffness
- Jerky movements (myoclonus)
- Loss of balance
Other Neurological Symptoms
- Vision problems
- Speech difficulty
- Swallowing impairment
- Rapid decline in daily functioning
Causes & Risk Factors
- Spontaneous prion misfolding
- Family history of prion disease
- Rare exposure through contaminated medical instruments
- Consumption of infected beef (variant CJD; very rare today)
How SSRC Diagnoses CJD
- Neurological examination
- MRI brain imaging with prion-specific patterns
- EEG to identify characteristic electrical brain activity
- Cerebrospinal fluid (CSF) testing, including RT-QuIC when indicated
- Genetic testing (for suspected familial cases)
- Ruling out treatable neurological disorders that mimic CJD
Take the First Step Toward Recovery
Schedule a consultation with our specialists today and start your journey to better health.
Treatment & Management at SSRC
Our care approach includes:
How SSRC Supports Patients & Families
- Clear, early diagnosis
- Transparent communication
- Holistic symptom management
- Emotional and decision-making support
- Coordination with neurology and internal medicine experts
- Long-term care planning
Frequently Asked Questions (FAQs)
No. CJD does not spread through casual contact, touch, air, or daily interactions.
CJD is typically fast-progressing, with noticeable changes occurring over months rather than years.
There is currently no cure, but early specialist care improves comfort, symptom management, and family preparedness.
Diagnosis involves MRI, EEG, CSF testing (such as RT-QuIC), and ruling out other neurological diseases.
Sporadic CJD occurs naturally and is most common; variant CJD is linked to contaminated beef exposure and is extremely rare.
A small percentage of cases are genetic and linked to inherited mutations in the PRNP gene.
If memory loss or coordination problems worsen quickly over weeks or months, seek immediate evaluation at SSRC
